MARINA - MAsks for Region of INterest Analysis 

Copyright (C) 2002 Bertram Walter Bender Institute of Neuroimaging University of Giessen, Germany email:

Bug reports, comments, and suggestions are highly appreciated. 

This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version.

This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License a the end of this file for more details.

You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA


MARINA allows you to create, smooth, threshold, edit, and save masks in an SPM-ANALYZE format. The creation of masks is aided by the anatomical parcellation of the brain published by Tzourio-Mazoyer et al. (2002). Voxel coordinates of brain structures come from their SPM toolbox AAL (automated anatomical labeling). AAL also provides the coordinates of cerebellar regions which were prepared by Schmahmann et al. (1999). Alternatively, masks generated by Nielsen and Hansen (2002) using the BrainMap database (Fox & Lancaster, 1994) can be downloaded ( and edited by MARINA. Resulting masks may be used for region of interest analysis of functional neuroimaging data in the small volume correction feature of SPM ( or elsewhere.

See the poster at HBM 2003 (pdf format, 334 KB) for more information. 


0.6        First public release
0.6.1     Fixed a bug in the analyze files. Now they can be used with SPM2.


MARINA comes as MARINA.ZIP (about 1.4 MB) which contains five files: 


MARINA doesn't need a installation procedure. Just extract the five files contained in MARINA.ZIP into the same directory. MARINA was written in DELPHI 6.0 on a Windows 2000 machine, it also works under Windows 98 and should run on all 32-bit Windows systems. Screen resolution should be at least 1024 x 768.

See README.txt for further instructions


Please cite MARINA with the following reference:

Walter, B., Blecker, C., Kirsch, P., Sammer, G., Schienle, A., Stark, R., & Vaitl, D. (2003). MARINA: An easy to use tool for the creation of MAsks for Region of INterest Analyses [abstract]. Presented at the 9th International Conference on Functional Mapping of the Human Brain, June 19-22, 2003, New York, NY. Available on CD-Rom in NeuroImage, Vol. 19, No. 2.